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Job Description

About the role:

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.

Join Takeda as a Research Associate II where you will perform research assignments and be responsible for high-throughput antibody production. You will also work on the discovery and engineering of therapeutic biologics including antibodies, antibody fragments, and fusion proteins. As part of the Biotherapeutic Engineering team, you will report to Scientist II, Biotherapeutic Engineering, where you will interpret and communicate results within the team and with cross-functional project team members.

How you will contribute:

• Independently conduct high-throughout antibody expression in yeast and purification using an automated system. Characterize the quantity and quality of the protein produced using a spectrometer and SDS PAGE.
• With support, execute discovery and lead optimization projects using display platform technologies with high quality and efficiency.
• Handle large datasets and analyze the data. Identify hits based on affinity, specificity, and potency.
• Isolate DNA/RNA, analyzing sequencing data.
• Thoroughly document experiments and communicate results within the team and cross-functional project teams.
• Initiate routine problem investigation and recommend solutions.
• Demonstrate technical knowledge of Molecular Biology and Biochemistry.
• Understand antibody structure and function, and the biologics discovery process.

Minimum Requirements/Qualifications:

• BS degree in a scientific discipline (or equivalent)
• Experience with protein expression and purification and an understanding of protein purification techniques is preferred.
• Skills in molecular biology including PCR, DNA/RNA isolation and purification, and cloning are highly desired.
• Experiences in antibody discovery and engineering are preferred.
• Experience with high-throughput antibody binding screens (ForteBio Octet, ELISA, flow cytometry) is highly desired.
• Experience with FACS sorting is highly desired.
• Experience with library construction is desired.
• Experience with yeast or other display library screening is preferred.
• Experience with graphing software such as GraphPad Prism and Excel is desired.
• Outstanding organizational skills and experience in preparing and presenting scientific data are preferred.

What Takeda can offer you:

• Comprehensive Healthcare: Medical, Dental, and Vision
• Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan
• Health & Wellness programs including onsite flu shots and health screenings
• Generous time off for vacation and the option to purchase additional vacation days
• Community Outreach Programs and a company match of charitable contributions
• Family Planning Support
• Flexible Work Paths
• Tuition reimbursement

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best-in-class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Base Salary Range: $63,700.00 to $81,900.00, based on the candidate's professional experience level. Employees may also be eligible for Short-term and Long-Term Incentive benefits as well. Employees are eligible to participate in Medical, Dental, Vision, Life Insurance, 401(k), Charitable Contribution Match, Holidays, Personal Days & Vacation, Tuition Reimbursement Program, and Paid Volunteer Time Off. The final salary offered for this position may take into account a number of factors including, but not limited to, location, skills, education, and experience.

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EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

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